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1.
Orv Hetil ; 159(42): 1700-1709, 2018 10.
Artigo em Húngaro | MEDLINE | ID: mdl-30334485

RESUMO

Dental amalgam has been used for more than 150 years due to its beneficial mechanical properties and durability in dentistry. In the past and to date, many questions about amalgam restorations have arisen, especially regarding the mercury content, which has been the subject of global disputes. By presenting the past and present of the 'amalgam issue', the aim of our paper is to display the current position of international literature. This summary is based on the publications in the PubMed database, the guidelines of the Council of European Dentists. Although the use of dental amalgam is widespread, concerns have been raised about the adverse effect on human health and the environment, focusing on its heavy metal pollution during waste treatment. In 2017, the European Union (EU) adopted the so-called Mercury Regulation, based on the United Nations Minamata Convention on Mercury, the recommendations of which are presented in the present review. This Regulation includes the requirement for EU Member States to develop a national action plan for the phase-down of amalgam. The feasibility plan for complete phase-out may be guaranteed by 2030. The authors discuss the advantages and disadvantages of possible amalgam alternatives by presenting glass-ionomers and resin-based composites. In the future, more material research programmes and long-term follow-up studies are necessary. In addition to several global health organizations, the Council of European Dentists also draws attention to prevent dental caries, expecting to reduce the number of restorations. Orv Hetil. 2018; 159(42): 1700-1709.


Assuntos
Resinas Acrílicas/uso terapêutico , Resinas Compostas/uso terapêutico , Amálgama Dentário/uso terapêutico , Restauração Dentária Permanente/métodos , Resinas Acrílicas/efeitos adversos , Resinas Compostas/efeitos adversos , Amálgama Dentário/efeitos adversos , Dentição Permanente , Humanos
2.
J Physiol Paris ; 109(4-6): 201-213, 2015 12.
Artigo em Inglês | MEDLINE | ID: mdl-26709191

RESUMO

Long-term photo-acoustic stimulation is used for the induction of altered states of consciousness for both therapeutic and experimental purposes. Long-term photo-acoustic stimulation also leads to changes in the composition of saliva which have a key contribution to the efficiency of this technique in easing mucosal symptoms of oral psychosomatic patients. The aim of this study is to find out whether there is any cumulative effect of repeated stimulation and whether there are any detectable differences between diverse stimulatory patterns of long lasting photo-acoustic stimulation on the phenomenology of the appearing trance state and on salivary secretion. There was significant cumulative effect in relation with the appearance of day dreaming as phenomenological parameter, and in relation with protein output and amylase/protein ratio as salivary parameter. Pattern specific effect was detectable in relation with salivary flow rate only. Although our results clearly indicate the existence of certain cumulative and stimulation-pattern specific effects of repeated photo-acoustic stimulation, the absolute values of all these effects were relatively small in this study. Therefore, in spite of their theoretical importance there are no direct clinical consequences of these findings. However, our data do not exclude at all the possibility that repeated stimulation with other stimulatory parameters may lead to more pronounced effects. Further studies are needed to make clear conclusion in this respect.


Assuntos
Estimulação Acústica , Estado de Consciência/fisiologia , Saliva/química , Saliva/enzimologia , Glândulas Salivares/fisiologia , alfa-Amilases/metabolismo , Humanos , Técnicas Fotoacústicas , Glândulas Salivares/enzimologia
3.
Fogorv Sz ; 108(1): 25-31, 2015 Mar.
Artigo em Húngaro | MEDLINE | ID: mdl-26117956

RESUMO

Altogether 4606 volunteers (2923 vomen, 1683 men) participated in the representative national epidemiological study to screen the alterations of temporomandibular joint (TMJ). The characteristic clinical signs and subjective complaints according to TMJ were evaluated by medical history taking and physical examination. Regarding the orthodontic anomalies, the vertical abnormalities (deep bite and open bite) were specifically noted. Clinical signs showing functional problems of TMJ were found in 45.19% of the screened population, mainly in the group of 35-44 year olds. The frequency of clicking and crepitation of TMJ was significantly higher in women compared to men (p < 0.05). The highest rate of clinical signs of TMJ disorders was found in the South-Transdanubian region, the lowest rate in the Middle-Transdanubian region, between these regions it was a significant difference regarding the frequency of deviation/deflexion (p < 0.05). Of the vertical abnormalities, deep bite occured most frequently in the 35-44 ys old age group. The prevalence of deep bite was higher among males than females in the whole screened population, but the difference was not statistically significant. Significant relationship was detected between deep bite and TMJ pain, deep bite and noises in the joint in the majority of the population. The most frequent anomaly in the South-Transdanubian region was deep bite, while the open bite occured most frequently in south middle part of Hungary. Conclusion: the Hungarian population needs well organized specific programs to improve the oral health including TMJ and orthodontic aspects.


Assuntos
Programas de Rastreamento , Mordida Aberta/epidemiologia , Transtornos da Articulação Temporomandibular/epidemiologia , Articulação Temporomandibular/anormalidades , Articulação Temporomandibular/fisiopatologia , Adulto , Distribuição por Idade , Idoso , Feminino , Necessidades e Demandas de Serviços de Saúde , Humanos , Hungria/epidemiologia , Incidência , Masculino , Programas de Rastreamento/métodos , Pessoa de Meia-Idade , Ruído , Mordida Aberta/patologia , Mordida Aberta/fisiopatologia , Saúde Bucal , Prevalência , Distribuição por Sexo , Transtornos da Articulação Temporomandibular/patologia , Transtornos da Articulação Temporomandibular/fisiopatologia , Síndrome da Disfunção da Articulação Temporomandibular/epidemiologia
4.
Int J Mol Sci ; 16(3): 5945-74, 2015 Mar 13.
Artigo em Inglês | MEDLINE | ID: mdl-25782158

RESUMO

The gustatory system plays a critical role in determining food preferences and food intake, in addition to nutritive, energy and electrolyte balance. Fine tuning of the gustatory system is also crucial in this respect. The exact mechanisms that fine tune taste sensitivity are as of yet poorly defined, but it is clear that various effects of saliva on taste recognition are also involved. Specifically those metabolic polypeptides present in the saliva that were classically considered to be gut and appetite hormones (i.e., leptin, ghrelin, insulin, neuropeptide Y, peptide YY) were considered to play a pivotal role. Besides these, data clearly indicate the major role of several other salivary proteins, such as salivary carbonic anhydrase (gustin), proline-rich proteins, cystatins, alpha-amylases, histatins, salivary albumin and mucins. Other proteins like glucagon-like peptide-1, salivary immunoglobulin-A, zinc-α-2-glycoprotein, salivary lactoperoxidase, salivary prolactin-inducible protein and salivary molecular chaperone HSP70/HSPAs were also expected to play an important role. Furthermore, factors including salivary flow rate, buffer capacity and ionic composition of saliva should also be considered. In this paper, the current state of research related to the above and the overall emerging field of taste-related salivary research alongside basic principles of taste perception is reviewed.


Assuntos
Saliva/metabolismo , Paladar , Humanos , Receptores Acoplados a Proteínas G/metabolismo , Proteínas e Peptídeos Salivares/metabolismo , Papilas Gustativas/metabolismo , Percepção Gustatória
5.
Int J Mol Sci ; 13(4): 4295-4320, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22605979

RESUMO

There are numerous defense proteins present in the saliva. Although some of these molecules are present in rather low concentrations, their effects are additive and/or synergistic, resulting in an efficient molecular defense network of the oral cavity. Moreover, local concentrations of these proteins near the mucosal surfaces (mucosal transudate), periodontal sulcus (gingival crevicular fluid) and oral wounds and ulcers (transudate) may be much greater, and in many cases reinforced by immune and/or inflammatory reactions of the oral mucosa. Some defense proteins, like salivary immunoglobulins and salivary chaperokine HSP70/HSPAs (70 kDa heat shock proteins), are involved in both innate and acquired immunity. Cationic peptides and other defense proteins like lysozyme, bactericidal/permeability increasing protein (BPI), BPI-like proteins, PLUNC (palate lung and nasal epithelial clone) proteins, salivary amylase, cystatins, prolin-rich proteins, mucins, peroxidases, statherin and others are primarily responsible for innate immunity. In this paper, this complex system and function of the salivary defense proteins will be reviewed.


Assuntos
Imunidade Adaptativa/imunologia , Imunidade Inata/imunologia , Mucosa Bucal/imunologia , Saliva/imunologia , Proteínas e Peptídeos Salivares/imunologia , Adrenomedulina/imunologia , Catelicidinas/imunologia , Defensinas/imunologia , Proteínas de Choque Térmico HSP70/imunologia , Histatinas/imunologia , Humanos , Imunoglobulina A/imunologia , Imunoglobulina M/imunologia , Lactoferrina/imunologia , Inibidor Secretado de Peptidases Leucocitárias/imunologia
6.
Fogorv Sz ; 105(1): 19-27, 2012 Mar.
Artigo em Húngaro | MEDLINE | ID: mdl-22530366

RESUMO

The aim of the authors was to investigate whether living as a minority has an influence on the dental fear and anxiety values. In this study 201 volunteers (n = 201, inside border Hungarians 144, outside border Hungarians 57, male 90, female 111; age 8 to 83 years, mean 44 +/- 16 yrs.) were investigated. Our methods included collection of demographic data (gender, age, marital status, profession), and administration of the Hungarian versions of dental fear and anxiety related scales namely: DAS, DAQ, DASQ, DFS, DBS, STAI-S, STAI-T and Expectation Scale. Mean values of the scales were: DAS: 10,34 +/- 3,54; DAQ: 2,3 +/- 1,15; DASQ: 12,58 +/- 4,55; DFS: 40,37 +/- 15,67; DBS: 32,89 +/- 12,94; Expectation Scale: 2,87 +/- 3,56, STAI-S: 39,51 +/- 10,68; STAI-T 41,65 +/- 9,08. The mean scores of all the scales were higher in the case of Hungarians living inside the borders of Hungary. The differences were significant in the case of DAS, DAQ, DASQ and DFS scales (p < 0,05). Data of our study indicate that living as a minority not necessarily leads to the increase of dental fear and anxiety.


Assuntos
Ansiedade ao Tratamento Odontológico/diagnóstico , Ansiedade ao Tratamento Odontológico/epidemiologia , Grupos Minoritários/estatística & dados numéricos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Feminino , Humanos , Hungria/epidemiologia , Masculino , Escala de Ansiedade Manifesta , Pessoa de Meia-Idade , Projetos Piloto , Eslováquia/epidemiologia , Inquéritos e Questionários
7.
Ann Ist Super Sanita ; 48(1): 49-52, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22456015

RESUMO

The aim of this study was to compare three different cone-beam CT (CBCT) instruments used in dental clinical practice with micro-CT as gold standard. Three female monkeys' (Macaca fascicularis) skulls were selected and scanned by the tested CBCT-s. The most apical visible root canal level on the CBCT images was used as reference level (RL). After the image acquisition by CBCT-s dental jaw sections were scanned by micro-CT at a resolution of 17 µm. Out of the left second and third molars 25 root canals were selected and analysed by three observers at RL and following cross sectional parameters were determined: area of the lumen, major and minor diameters, aspect ratio and mean thickness. Results suggest that only high resolution CBCT instruments allow dentists detecting the full length of the root canal.


Assuntos
Tomografia Computadorizada de Feixe Cônico/instrumentação , Cavidade Pulpar/diagnóstico por imagem , Imageamento Tridimensional/instrumentação , Odontometria/métodos , Microtomografia por Raio-X/instrumentação , Animais , Tomografia Computadorizada de Feixe Cônico/métodos , Cavidade Pulpar/ultraestrutura , Feminino , Imageamento Tridimensional/métodos , Técnicas In Vitro , Macaca fascicularis , Dente Molar/diagnóstico por imagem , Dente Molar/ultraestrutura , Variações Dependentes do Observador , Microtomografia por Raio-X/métodos
8.
J Mater Sci Mater Med ; 23(3): 677-85, 2012 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-22286280

RESUMO

Discs of biocompatible glass ionomer cements were prepared for Hertzian indentation and subsequent fracture analyses. Specifically, 2 × 10 mm samples for reproducing bottom-initiated radial fracture, complemented by 0.2 × 1 mm samples for optimal resolution with X-ray micro tomography (µCT), maintaining dimensional ratio. The latter allowed for accurate determination of volumetric-porosity of the fully cured material, fracture-branching through three Cartesian axes and incomplete bottom-initiated cracking. Nanocomputed tomography analyses supported the reliability of the µCT results. Complementary 2-dimensional fractographic investigation was carried out by optical and scanning electron microscopies on the larger samples, identifying fracture characteristics. The combined 3-D qualitative assessment of microstructure and fractures, complemented by 2-D methods, provided an increased understanding of the mechanism of mechanical failure in these cements. Specifically, cracks grew to link pores while propagating along glass-matrix interfaces. The methodological development herein is exploitable on related biomaterials and represents a new tool for the rational characterisation, optimisation and design of novel materials for clinical service.


Assuntos
Materiais Biocompatíveis , Vidro , Tomografia por Raios X/métodos
9.
Fogorv Sz ; 104(1): 3-8, 2011 Mar.
Artigo em Húngaro | MEDLINE | ID: mdl-21789930

RESUMO

A representative national survey by the dentists of the Department of Prosthodontics, Semmelweis University was performed to assess oral health conditions of Hungarian adult population before joining the European Union. The aim of this study was to evaluate periodontal conditions of the population from data collected in the survey and to investigate the associations between gender, age and demographic regions and the prevalence of periodontal problems. The 2 years long nationwide investigation followed the WHO criteria (World Health Organization, 1997) and assessed 4606 person throughout all regions of the country. Periodontal conditions and treatment needs of 4153 person were assessed in intraoral examinations by Community Periodontal Index (CPI) method. Age, gender, demographic regions were recorded on questionnaires. According to our findings CPI 2 was the most frequent finding in all age groups which primarily reflected poor oral hygiene. When we consider gender differences, CPI 3 and CPI 4 were more frequent among males while women had CPI 0 and CPI 2 with higher frequency. Our findings reflect regional differences of periodontal health conditions as 16% of the population of the capitol and its surroundings had healthy periodontal condition however we could find CPI 0 only in 5-8% of Middle and South-Danubium population. Findings of our epidemiologic survey call attention on poor oral hygene of the population. There is a need in Hungary for better oral health education of the population, more preventive programs and action plans to promote regular dental office attendance.


Assuntos
Cárie Dentária/epidemiologia , Educação em Saúde Bucal , Saúde Bucal , Índice de Higiene Oral , Higiene Bucal , Doenças Periodontais/epidemiologia , Índice Periodontal , Adulto , Distribuição por Idade , Inquéritos de Saúde Bucal , Feminino , Necessidades e Demandas de Serviços de Saúde , Humanos , Hungria/epidemiologia , Masculino , Prevalência , Distribuição por Sexo , Inquéritos e Questionários
10.
Fogorv Sz ; 104(2): 39-47, 2011 Jun.
Artigo em Húngaro | MEDLINE | ID: mdl-21789934

RESUMO

In this study, risk determinants were assessed for periodontal disease in the oral health survey of a representative Hungarian adult population sample. 4153 individuals participated in the study after formal consent. Participants were questionned on level of education, dental office attendance, smoking habits, oral hygiene habits and general health conditions. Quality of fixed partial dentures (FPD) were evaluated. Periodontal health status was assessed with the CPI method according to WHO criteria. When the prevalence of CPI scores was assessed by educational level, significant differences were found between groups. With increasing levels of education, a significantly higher percentage of subjects visited the dental office regularly. Higher prevalence of CPI 0 was found among those with higher level of education but there was also high prevalence of CPI 2, representing bad oral hygiene in the highly educated group. Findings of our study showed high percentage (66%) of the population attending the dental office only in case of emergency. The investigation revealed destructive effect of unsatisfactory construction of FPD on the periodontium. Healthy periodontium (CPI 0) was found among 16% of those wearing no FPD and 9% among FPD-wearers. The prevalence of deep periodontal pockets (CPI 4) was 1,6 times higher among smokers as non-smokers. Oral health statistics play an important role in planning for improvement of dental health care. Hungary needs effective prevention programs and emphasize on regular dental office attendance of individuals to improve the nation's oral health status.


Assuntos
Saúde Bucal , Higiene Bucal , Doenças Periodontais/epidemiologia , Adulto , Inquéritos de Saúde Bucal , Escolaridade , Feminino , Educação em Saúde Bucal , Necessidades e Demandas de Serviços de Saúde , Nível de Saúde , Humanos , Hungria/epidemiologia , Masculino , Visita a Consultório Médico/estatística & dados numéricos , Higiene Bucal/métodos , Índice de Higiene Oral , Doenças Periodontais/prevenção & controle , Índice Periodontal , Prevalência , Medição de Risco , Fatores de Risco , Fumar/efeitos adversos , Inquéritos e Questionários
11.
J Dent ; 38 Suppl 2: e41-9, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20659524

RESUMO

OBJECTIVES: The aim of this study was to evaluate whether simulated severe red and green color vision deficiency (CVD) influenced color matching results and to investigate whether training with Toothguide Trainer (TT) computer program enabled better color matching results. METHODS: A total of 31 color normal dental students participated in the study. Every participant had to pass the Ishihara Test. Participants with a red/green color vision deficiency were excluded. A lecture on tooth color matching was given, and individual training with TT was performed. To measure the individual tooth color matching results in normal and color deficient display modes, the TT final exam was displayed on a calibrated monitor that served as a hardware-based method of simulating protanopy and deuteranopy. Data from the TT final exams were collected in normal and in severe red and green CVD-simulating monitor display modes. Color difference values for each participant in each display mode were computed (∑ΔE(ab)(*)), and the respective means and standard deviations were calculated. The Student's t-test was used in statistical evaluation. RESULTS: Participants made larger ΔE(ab)(*) errors in severe color vision deficient display modes than in the normal monitor mode. TT tests showed significant (p<0.05) difference in the tooth color matching results of severe green color vision deficiency simulation mode compared to normal vision mode. Students' shade matching results were significantly better after training (p=0.009). CONCLUSIONS: Computer-simulated severe color vision deficiency mode resulted in significantly worse color matching quality compared to normal color vision mode. Toothguide Trainer computer program improved color matching results.


Assuntos
Defeitos da Visão Cromática , Planejamento de Prótese Dentária/instrumentação , Diagnóstico por Computador/instrumentação , Pigmentação em Prótese/normas , Descoloração de Dente/diagnóstico , Adulto , Cor/normas , Simulação por Computador , Instrução por Computador , Aprendizagem por Discriminação , Feminino , Humanos , Masculino , Valores de Referência , Estudantes de Odontologia , Descoloração de Dente/classificação , Adulto Jovem
12.
Fogorv Sz ; 103(4): 131-9, 2010 Dec.
Artigo em Húngaro | MEDLINE | ID: mdl-21268394

RESUMO

AIM: To investigate if there is an influence of being a disabled people (with disturbed body-image), dental fear and anxiety on several form/shape parameters of drawings. SUBJECTS: Disabled (46) and healthy (33) volunteers (n = 79; male 39, female 40; age: 18.16 +/- 3.01 yrs.) were investigated. METHODS: Collection of demographic data (gender, age, marital status, profession), and administration of the Hungarian versions of dental fear and anxiety related scales namely: DAS, DAQ, DASQ, DFS, DBS, STAI-S, STAI-T and Expectation scale. Free drawing test portraying a person, a mouth, and a tooth were also administered, and form/shape parameters were analyzed. RESULTS: Mean values of the scales were: DAS: 10.22 +/- 3.1; DAQ: 2.21 +/- 0.9; DASQ: 12.44 +/- 3.9; DFS: 40.98 +/- 14,0; Expectation Scale: 2.32 +/- 0.7, DBS: 34.50 +/- 9.0; STAI-S: 37.56 +/-10.7; STAI-T 42.41 +/-10.2. Disables subjects scored higher in all of the scales but there was a significant difference (t-probe, p < 0.05) in the case of DBS scale only. Being a disabled influenced 2 of person-, 5 of tooth-, and 3 of mouth-drawing parameters significantly (chi2 probe, p < 0.05). Dental fear related scales influenced 5 of person-, 5 of tooth-, and 1 of mouth-drawing parameters significantly (one-way ANOVA, p < 0.05). Anxiety influenced 2 of person-, 1 of tooth-, and none of mouth-drawing parameters significantly (one-way ANOVA, p < 0.05). CONCLUSION: Interestingly, the influence of being a disabled people was the strongest in case of tooth-drawings, and the influence of dental fear on drawing parameters was stronger than that of anxiety.


Assuntos
Arteterapia , Ansiedade ao Tratamento Odontológico/diagnóstico , Ansiedade ao Tratamento Odontológico/psicologia , Pessoas com Deficiência/psicologia , Adolescente , Estudos de Casos e Controles , Feminino , Humanos , Masculino , Distribuição por Sexo , Inquéritos e Questionários , Adulto Jovem
13.
Artigo em Inglês | MEDLINE | ID: mdl-19778746

RESUMO

OBJECTIVE: The aim of this study was to assess quantitatively the degrading effect of artefacts caused by beam hardening on the microscopic computerized tomography (microCT) measurements of an in vitro caries model. STUDY DESIGN: A simulation-based method was described, with which the degrading effect of microCT artefacts on certain parameters of the observed structure could be determined. Simulations were carried out with polychromatic and monochromatic X-ray source, and a linearization method with a second-order polynomial fit algorithm was used in specific cases to correct the beam hardening artefact. The virtual test object was a half-crown of a tooth with an artificial caries lesion. RESULTS: For simulation with monochromatic X-ray source, the relative error of lesion depth and thickness measurements of the remineralized layer was found to be 1%-2%. For polychromatic X-ray source, and omitting beam hardening correction, the relative error exceeded 6%. After appropriate beam-hardening correction, the relative error of the measurement could be reduced to 1%-2%. CONCLUSION: With the adjustment simulated in this study, microCT having polychromatic X-ray source resulted in the same level of error as with monochromatic source if the linearization method to correct the beam hardening was used. The presented simulation-based method is a useful way to determine artefact-caused distortions for other studies testing objects with different material and geometry.


Assuntos
Artefatos , Cárie Dentária/diagnóstico por imagem , Microtomografia por Raio-X/métodos , Algoritmos , Fenômenos Biofísicos , Simulação por Computador , Esmalte Dentário/diagnóstico por imagem , Cavidade Pulpar/diagnóstico por imagem , Dentina/diagnóstico por imagem , Humanos , Modelos Biológicos , Modelos Teóricos , Método de Monte Carlo , Imagens de Fantasmas , Intensificação de Imagem Radiográfica/métodos , Espalhamento de Radiação , Coroa do Dente/diagnóstico por imagem , Remineralização Dentária , Raios X
14.
J Clin Periodontol ; 36(6): 449-57, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19508245

RESUMO

OBJECTIVES: To estimate the levels of periodontal health conditions of Hungarian adults. MATERIAL AND METHODS: Periodontal data on 4153 adults in 304 survey locations from all Hungarian regions were analysed. The Community Periodontal Index (CPI) was used to report the occurrence of probing pocket depth, calculus, and gingival inflammation. Age, gender, socioeconomic and health status, oral hygiene and lifestyle habits, dental office attendance, level of education, and fixed partial denture (FPD) treatment were evaluated for their association with periodontal conditions. CPI score as an outcome was dichotomized using an accepted threshold as low (<3) and high (3, 4) for multiple logistic regression modelling. RESULTS: CPI2 was the most prevalent score in all age groups. CPI scores were also strongly associated with the independent variables. Approximately 66% of subjects visited a dentist only in the case of an emergency. Lack of periodontal aspects of restorative care was demonstrated by the result of CPI0 among 16% of non-FPD wearers compared with only 9% of individuals treated with FPD. CONCLUSION: The present survey indicates that oral hygiene standards and periodontal health conditions need improvement in Hungary. Effective intervention programme for the prevention and control of periodontal disease are recommended at a national level.


Assuntos
Doenças Periodontais/epidemiologia , Adolescente , Adulto , Fatores Etários , Idoso , Cálculos Dentários/epidemiologia , Assistência Odontológica/estatística & dados numéricos , Prótese Parcial Fixa/estatística & dados numéricos , Escolaridade , Feminino , Gengivite/epidemiologia , Nível de Saúde , Humanos , Hungria/epidemiologia , Estilo de Vida , Masculino , Pessoa de Meia-Idade , Higiene Bucal/estatística & dados numéricos , Índice Periodontal , Bolsa Periodontal/epidemiologia , Prevalência , Fatores Sexuais , Fumar/epidemiologia , Classe Social , Adulto Jovem
15.
Pathol Oncol Res ; 15(4): 567-77, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19267222

RESUMO

Bisphosphonates are widely used as therapeutic agents in bone disorders including cancer metastasis due to their osteoclast inhibitory effect. Recent data shows that bisphosphonates may also induce bone-building by stimulating osteoblast activity. Clinical observations, however, have revealed that bisphosphonates may cause necrosis in the oral cavity which questions their usefulness in bone regeneration during the consolidation of inorganic implants. Here we report the investigation of bone neogenesis following chronic amine bisphosphonate (Zometa) treatment in a novel experimental model, using the rat tail vertebra as a support. This method involves (1) implantation of titan screw into the tail vertebrae, (2) systemic bisphosphonate treatment and (3) quantitative biophysical measurements which mirrors consolidation of implant, i.e. strength of fixation and changes in newly formed bone architecture using micro Computer Tomograph (micro-CT). The degree of fixation of titan implants (osseointegration) increased by 36% on the effect of Zometa and the structure of newly formed bone became robust. The mass of new bone increased 3.1-fold at 6 weeks of regeneration, as compared to controls. Thus, Zometa, a potent aminobisphosphonate used in therapy of cancer metastases, osteoporosis and bone marrow transplantation, significantly increased bone neogenesis and enforced osseointegration of titan implants as measured quantitatively in the rat tail vertebra. Our data support the usefulness of aminobisphosphonates in the rehabilitation of bone loss as well as in improvement osseointegration of implants. We emphasise that this novel method may open up new possibilities for screening the effects of local and systemic treatments.


Assuntos
Conservadores da Densidade Óssea/farmacologia , Regeneração Óssea/efeitos dos fármacos , Difosfonatos/farmacologia , Imidazóis/farmacologia , Implantação de Prótese , Cauda , Titânio , Vertebrados/cirurgia , Animais , Fenômenos Biomecânicos , Parafusos Ósseos , Feminino , Modelos Animais , Ratos , Ratos Wistar , Cauda/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Ácido Zoledrônico
16.
Fogorv Sz ; 101(5): 171-8, 2008 Oct.
Artigo em Húngaro | MEDLINE | ID: mdl-19039918

RESUMO

There are only a few factors, where the properties of the CBCT is inferior compared to conventional CT. One of these properties is the low contrast resolution, which has an importance in the discrimination of different soft tissues. Another difference is the image quality degrading effect by metal objects. This latter factor has much higher importance in head and neck region CBCT application. The metal artifact is closely related to other types of artifacts, like beam-hardening and x-ray photon scattering artifacts. In some of the cases, metal artifacts can be avoided by the proper adjustment of the scanning parameters, but sometimes the problem overgrows the possibilities. The current pre- and post-processing algorithms used for the correction of different artifacts can improve the image quality, but these algorithms are not the ultimate solution to the problem. The introduction of iterative reconstruction algorithms into the CBCT market will effectively reduce the most CT artifacts, however, the spread of this algorithms are set back because of the insufficient computational power of today's PCs. Another advantage of the use of iterative algorithms is that the patient dose could be significantly reduced.


Assuntos
Artefatos , Tomografia Computadorizada de Feixe Cônico , Cabeça/diagnóstico por imagem , Metais , Pescoço/diagnóstico por imagem , Algoritmos , Humanos , Imagens de Fantasmas , Doses de Radiação , Intensificação de Imagem Radiográfica , Interpretação de Imagem Radiográfica Assistida por Computador
17.
BMC Public Health ; 8: 364, 2008 Oct 21.
Artigo em Inglês | MEDLINE | ID: mdl-18939981

RESUMO

BACKGROUND: Oral health is basically important for the well-being of people. Thus, it is strongly suggested to organize epidemiological surveys in order to gain representative data on oral condition of the given population. The purpose of the cross-sectional study was to determine the results on tooth loss and caries prevalence of Hungarian adults in different age groups. METHODS: Altogether 4606 persons (2923 women, 1683 men) participated in the study who were classified into different age groups: 19 [less than or equal to], 20-24, 35-44, 45-64, 65-74, [greater than or equal to]75 year olds. Probands were selected randomly from the population attending the compulsory lung screening examinations. The participants were examined by calibrated dentists, according to the WHO (1997) criteria. In order to produce representative data, the chosen localities for these examinations covered the capital, the largest towns, the villages, and case weights were used for the statistical evaluation. RESULTS: The mean values of DMF-T were found between 11.79+/-5.68 and 21.90+/-7.61 These values were significantly higher in women compared to men (p < 0.05). In all age groups the values of M were the highest. Except for the women in the groups of 35-44 and 45-64 year olds, these values showed an increasing tendency both in women and men by age (from 5.50+/-6.49, and 4.70+/-4.08 to 21.52+/-9.07 and 18.41+/-8.89 respectively). The values of D components reached the highest values in 45-64 year olds (4.54+/-2.12 and 4.22+/-2.81, by gender, respectively), then in the older age groups there was a high reduction in these values (in 65-74 year olds: 2.72+/-1.88 and 1.36+/-2.48; in 75 or more than 75 year olds: 1.05+/-1.41 and 1.03+/-1.76 by gender, respectively). The ratio of D and F values was the highest in the age group of 65-74 year olds (2.12), the lowest ratio could be calculated in 20-34 year olds (0.65).Data showed some decrease in caries experience in 35-44 years of age between 2000 and 2004. The prevalence of persons with 21 or more teeth had been increased from 65.6% to 73.1%. This positive tendency has not been occured in prevalence of edentulousness in this age group: the prevalence of edentulous persons changed from 1.4 to 1.9%. In 65-74 year olds the level of edentulousness became lower, from 25.9 to 14.8% and the prevalence of persons with 21 or more teeth is higher (22.6%) than it was in 2000 (13.0%). CONCLUSION: Present data from Hungary show some slight decrease in caries experience between 35-44 years of age, although this positive tendency has not been occured in prevalence of edentulousness in this age group. A positive tendency could be experienced in the group of 65-74 year olds in edentulousness and in number of teeth, but further efforts are needed to reach a better situation.


Assuntos
Cárie Dentária/epidemiologia , Perda de Dente/epidemiologia , Adulto , Idoso , Estudos Transversais , Feminino , Inquéritos Epidemiológicos , Humanos , Hungria/epidemiologia , Masculino , Pessoa de Meia-Idade , Adulto Jovem
18.
Fogorv Sz ; 101(1): 3-11, 2008 Feb.
Artigo em Húngaro | MEDLINE | ID: mdl-18488739

RESUMO

Removable partial dentures (RPD) are used to restore Class 2A, 2B, 2A/1, and Class 3 type partially edentulous arches. Calibrated dentists of the Department of Prosthodontics performed oral health survey first in 1985-1989 and a second survey in 2003-2004. The oral surveys were carried out at the lung cancer screening stations, after obtaining formal consent of those individuals who were originally referred to perform x-ray lung screening examination. Subjects were interviewed and clinically examined under artificial lighting conditions. In the "second" survey data collected on 765 RPDs were analysed. Examined aspects of RPD design were: the protection of the marginal periodontium, extension of major connectors, base plate materials, tooth and tissue support. The level of restoration related damage on the remaining teeth was estimated according to whether remaining teeth were used for retention or for support; had any other type of denture-contact or remaining teeth were free from contact with denture. Approximately 50% of dentures showed dento-mucosal or muco-dental support; metal base was present in 45-48% of dentures; 47% of major connectors were designed with reduced extension; freedom of gingival margin was assured in 43-45% of the dentures. 26.10% of reference teeth; 19.11% of the remaining teeth used for support; 31.53% of the teeth used for retention; 28.07% of the teeth free from contact with denture and 38.00% of those remaining teeth with any other type of denture contact showed a sign of damage. Findings of the authors' survey show a considerable improvement in all aspects of RPD design--but still further progression is required. Those principles of RPD design taught in dental schools can only gradually influence the routine daily dental practice. Assessment of remaining teeth damages confirm the standards we outlined for RPD design with the main priorities of dental support and the protection of the gingival margin.


Assuntos
Planejamento de Dentadura , Prótese Parcial Removível , Dente/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Dente Suporte , Grampos Dentários , Bases de Dentadura , Encaixe de Precisão de Dentadura , Feminino , Humanos , Hungria , Masculino , Mandíbula , Maxila , Pessoa de Meia-Idade , Doenças Periodontais/prevenção & controle , Índice Periodontal , Inquéritos e Questionários , Fatores de Tempo
19.
Fogorv Sz ; 101(1): 29-32, 2008 Feb.
Artigo em Húngaro | MEDLINE | ID: mdl-18488742

RESUMO

In Hungary a dental epidemiological study was performed by a team of calibrated dentists of the Department of Prosthetic Dentistry (Semmelweis University, Budapest) in 1985-89 for the first and in 2003-2004 for the second time. Probands were selected randomly from the population attending the compulsory lung screening examinations. Oral inspection was done under artificial light. Data were immediately entered into computer on the spot. In the first epidemiological study after the examination of 9991 people we have found 1625 cantilever bridges, in the second study we examined 4606 people, and we have found 878 cantilever bridges. In 1989 66.9% of the cantilever bridges replaced missing tooth on the mesial and 33.1% on the distal end. In 2004 44.5% of the cantilever bridges replaced missing tooth on the mesial and 55.5% on the distal end. In both investigations one pontic distal cantilevers were the majority of restorations. In the study of 1989 we have found the highest number of the bridges with one distal pontic supported by two abutments. In the 2004 study the most frequently found one pontic distal cantilever bridges were supported by more then two abutments. Both investigations found the most distal cantilever bridges in the upper jaw replacing the first molar (32%, 38%), then the second molar (20%, 28%), and first premolar (18%, 20%). On the lower jaw distal cantilever pontics were replacing first molars in most of the cases (61%, 59%), then second premolars (19%, 24%) and first premolars (8%, 9%). In both investigations most frequently free end saddle (74%, 83%), remaining teeth (19%, 16%), crowns and artificial teeth distally from the cantilever pontic have been found.


Assuntos
Dente Suporte , Planejamento de Dentadura , Retenção de Dentadura , Prótese Parcial Fixa/estatística & dados numéricos , Maxila , Dente Molar , Adulto , Idoso , Prótese Parcial , Feminino , Humanos , Hungria/epidemiologia , Masculino , Pessoa de Meia-Idade
20.
Fogorv Sz ; 100(3): 91-7, 2007 Jun.
Artigo em Húngaro | MEDLINE | ID: mdl-17695044

RESUMO

The aim of the study was to reveal the oral hygienic, nutritional and behavioral habits of Hungarian adult population in different regions of Hungary. The study was performed by the Department of Prosthetic Dentistry (Semmelweis University, Budapest) in 2003-2004. Altogether 4606 persons (mean age: 46.37 +/- 7.89ys), 2923 women (mean age: 48,09 +/- 18,36 ys), 1683 men (mean age: 44.41 +/- 17.14 ys) participated in the study. Probands were selected randomly from the population attending the compulsory lung screening examinations. To make a representative sample of the whole population in the country, the chosen localities covered all regions, the capital, the large towns and villages as well. The data were coded on special sheets by computer in place. Statistical analysis was performed using SPSS for Windows 10.0 statistical software version. The daily consumption of sweets was the highest (34%) in the Western Central Region. It was the highest in the age group under 19 ys (40%). In relation to daily consumption of coke and soft drinks, the frequency was 13% in the whole population. The highest frequency was registered in the North Eastern Region (17.5%) and in the age group of 19-year-olds. The results showed that the consumption of soft drinks was significantly lower in women comparing to men (p < 0.001). The consumption of sweets and soft drinks was significantly decreased by the increase of age (p < 0.001). The asked population cleaned their teeth twice a day, mostly using only toothbrush and dentifrice, and only 12% of them used mouthwash, 11% toothpick, and 7% dental floss. The majority of the examined population (68%) visited dental service on an irregular base (only in case of acute complaints).


Assuntos
Assistência Odontológica/estatística & dados numéricos , Comportamento Alimentar , Visita a Consultório Médico/estatística & dados numéricos , Higiene Bucal/estatística & dados numéricos , Adulto , Bebidas Gaseificadas/estatística & dados numéricos , Estudos Transversais , Feminino , Pesquisas sobre Atenção à Saúde , Humanos , Hungria/epidemiologia , Masculino , Pessoa de Meia-Idade , Higiene Bucal/instrumentação , Inquéritos e Questionários
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